Isy-Calm is an innovative pharmaceutical device for the treatment of ulcers and aphtae in the mouth. The Isy-Calm applicator designed by Pilipili NV contains a precision applicator system. This patented system makes it possible to contain 40 doses of 0.05 ml in a very compact and small product. The Isy-Calm pen applicator is a clean and hygienic product made of two components: PP + TPE (Polypropylene and Thermoplastic Elastomers).