The Chilote Shoe is a design-craft product made 100% by hand in the Chilean Patagonia using only repurposed and up-cycled salmon leather and natural wool. This simple, noble, extremely comfortable and highly sustainable indoor shoe redefines the concept of inclusive design and conscious consumption. It is the result of the synergy created by three valuable assets; design guided craftsmanship, noble renewable materials from the Patagonia, and a disruptive socially inclusive manufacturing ecosystem. The challenge was to create a highly sustainable opportunity that redefines the meaning of social inclusiveness, eco-materials and processes as well as what is desirability and commercial viability. In this context, we needed to go beyond the traditional limitations imposed on sustainability measures of current manufacturing practices where incremental steps allow only small iterative improvements. Instead, we began focusing on the most eco-friendly materials and production methods available that were compatible with the local craftsmanship and social realities. Those limitations turned out to be the enablers of the Chilote House Shoe's universal appeal not only for it's aesthetic and functional qualities but also by providing a highly innovative story-line that embraces sustainability'